Neurohumoral Transmission in CNS

 Neurohumoral Transmission in CNS

The term neurohumoral transmission designates the transfer of a nerve impulse from a presynaptic to a postsynaptic neuron by means of a humoral agent e.g. a biogenic amine, an amino acid or a peptide.

Chemical substance which is released at the end of a nerve fibre by the arrival of a nerve impulse and, by diffusing across the synapse or junction, effects the transfer of the impulse to another nerve fibre, a muscle fibre, or some other structure.

Lifecycle of Neurotransmitter

Neurotransmitters mode of action

Chemical Mediators in CNS

Biogenic ->       Serotonin, Histamine, Adrenaline, Noradrenaline,                                  Dopamine

Amino Acids->     Glutamate, Aspartate, GAMA, Glycine

Neuro Modulators ->     Neuropeptide-y, Substance-p

Lipid Mediators->    Prostaglandins